What is Insulin Resistance?
Insulin resistance is a pathological condition in which cells fail to respond normally to the hormone insulin [Wiki]. Insulin is produced by pancreas, an important organ of your body. Insulin helps open the door of cells so that glucose (sugar) can enter into cells to create energy. For better understanding, when glucose starts to be released into the bloodstream from the digestion of carbohydrates in the diet, pancreas produces insulin which knocks at the door of cells to let glucose get into cells to be used for energy, and inhibits the body from using fat for energy. If this process will continue in its normal way, then the glucose level in the blood stream will remain normal. But the problem is there when cells fail to respond to the hormone insulin. That means pancreas produces insulin but it can’t let glucose get into cells to be used for energy due to dysfunction of cells’ door. If you suffer from this complexity, it indicates you are suffering from insulin resistance. This article is a detailed discussion on the issue, read and find great ways about the treatment for insulin resistance.
When you suffer from this complexity, your pancreas increases production of insulin contributing to a high blood insulin level. You may not understand the matter and remain undetected of the fact. In such case, you can contribute to a diagnosis of type 2 diabetes or insulin resistance test; if detected, you should go for a treatment for insulin resistance.
Symptoms of insulin resistance:
Insulin resistance may be your hidden enemy because it may not be understood in the early stage. So it is difficult to determine when you should go for a treatment for insulin resistance? You may be an insulin resistant for years but you will not understand if your blood glucose levels aren’t checked. For ready reference, normal blood sugar is up to 99 milligrams per deciliter (mg/dL). Symptoms of insulin resistance may not be apparent but in the case of type 2 diabetes or metabolic syndrome, some symptoms may appear which are common like:
- Weakness and fatigue.
- Poor mental stamina, sleepiness and drowsiness during the day time.
- Increased thirst, frequent urination, increased hunger, and weight gain or weight loss.
- Raised blood pressure.
- Overweight or obesity
Here is a table provided by Medscape, where you will find what normal insulin levels or regular insulin levels you should have.
Reference Range of Insulin Levels or Regular Insulin Levels
|Insulin Level||Insulin Level (SI Units*)|
|Fasting||< 25 mIU/L||< 174 pmol/L|
|30 minutes after glucose administration||30-230 mIU/L||208-1597 pmol/L|
|1 hour after glucose administration||18-276 mIU/L||125-1917 pmol/L|
|2 hour after glucose administration||16-166 mIU/L||111-1153 pmol/L|
|≥3 hours after glucose administration||< 25 mIU/L||< 174 pmol/L|
|*SI unit: conversional units x 6.945|
Insulin resistance and type 2 diabetes:
Where there is insulin resistance, there is type 2 diabetes. If cells of your body fail to respond to the insulin, it indicates insulin resistance. For more clarify, when you are suffering from insulin resistance, your muscle, fat, and liver cells can’t absorb glucose from the bloodstream. At this point, your body requires higher levels of insulin. The beta cells in the pancreas try to keep up with this increased demand of insulin, and produce more insulin to keep blood glucose levels in normal. But the problem is when your body, specially your muscle, fat, and liver cells can’t absorb glucose from the bloodstream and glucose builds up in the blood stream, it may be a symptom of type 2 diabetes which indicates high levels of glucose in the blood. It is also called the insulin resistance type 2 diabetes.
How high your blood glucose levels indicate whether you have diabetes: Normal blood sugar is up to 99 milligrams per deciliter (mg/dL). Prediabetes (impaired fasting glucose) is diagnosed if blood sugar is from 100 to 125 mg/dL. Diabetes is diagnosed if blood sugar is 126 mg/dL or higher.
Insulin Resistance and Excess Weight:
According to specialists, obesity, particularly excess fat around the waist, is a primary cause of insulin resistance which is also called insulin resistance type 2 diabetes. It is said that fat tissue functions solely as energy storage. Studies have shown that belly fat produces hormones and other substances that can cause serious health problems including insulin resistance type 2 diabetes, high blood pressure, imbalanced cholesterol, and cardiovascular disease (CVD).
Belly fat can play a vital role in developing chronic, or long-lasting, inflammation in the body. This chronic inflammation can damage the body over time, without any signs or symptoms. It is believed that complex interactions in fat tissue draw immune cells to the area and trigger low-level chronic inflammation. If you have such inflammation, it can contribute to the development of insulin resistance type 2 diabetes, and CVD.
Physical Inactivity can cause type 2 diabetes insulin resistance:
Physical inactivity is considered to be a major factor that can lead to type 2 diabetes insulin resistance as well. In your body, a number of glucose are used by muscle than other tissues. Generally, active muscles burn their stored glucose for energy and refill their reserves with glucose taken from the bloodstream and keep your blood glucose levels in normal. So physical inactivity can lead to type 2 diabetes insulin resistance.
Exercise is the best of insulin resistance treatments:
Instead of medications, there are different ways on how to cure insulin resistance. These ways can help your body cells to make more receptive to insulin though it is difficult to defeat insulin resistance entirely. If you feel above symptoms of insulin resistance within you, you should become active and take an insulin resistance test. It will help you the best for reducing rigorous impact of insulin resistance. Among different insulin resistance treatments, exercise is the best. If you want to apply tricks on how to cure insulin resistance, practice regular exercise for 15 to 30 minutes. When your body is active for conducting different physical works, it opens up an alternate gateway for glucose to enter into your body cells, especially your muscle cells. In this case, the cells don’t depend on insulin. This way will tremendously control your blood glucose level.
Experts say that losing the weight can reduce insulin resistance and it is possible through regular exercise. Studies show that after exercising, muscles become more sensitive to insulin, reversing insulin resistance and lowering blood glucose levels. Exercise also helps muscles absorb more glucose without the need for insulin. The more muscle a body has, the more glucose it can burn to control blood glucose levels.
Researchers show that eating low fat food and high quality carbohydrates can worsen insulin resistance. They have also shown that people who undergo weight-loss surgery are likely to become significantly more sensitive to insulin which is one of the symptoms of insulin resistance. While no medications are able to cure insulin resistance, exercise is the best of insulin resistance treatments. Yet diabetes medications are insulin sensitizers that lower blood glucose, at least in part, by reducing insulin.